Clinical efficacy of nivolumab is associated with tertiary ...
· Tertiary lymphoid structures (TLS), aggregates of various immune cells around B cells, are structurally and functionally similar to secondary lymph organs, and function as antigenpreserving cells and activate T cells [12, 13]. TLS are associated with antitumor immune responses and good prognosis in several cancers [14–16]. We also previously reported that .